I recently stumbled across a Let's Play video on YouTube for a game called Uncraft Me. It's a 2D platformer with an art style that somehow manages to combine Minecraft with hentai dating sims.
The player is tasked with freeing nine goddesses who have been trapped in ice. Each level is essentially a vertical obstacle course with one of the gigantic goddesses in the background. Your goal is to climb upward with your trusty jetpack, firing missiles along the way to break through the wall of ice and free the giant girl.
I've only played the demo so far, but it seems like a fun, challenging game. The giantess angle is mostly just icing on the cake.